Benton Labs

About Dr. H. Paul Benton

With over 15 years of experience in bioinformatics and data science, I specialize in transforming complex biological data into actionable insights for drug discovery and scientific research.

My background spans proteomics, metabolomics, and advanced computational biology, having led teams at Vicinitas, Denali Therapeutics, and Scripps Research Institute.

I hold a PhD in Biochemistry/Bioinformatics from Imperial College London and have published groundbreaking work in metabolomics data analysis, including the widely-used XCMS platform.

Core Expertise

Multi-omics Data Integration
Machine Learning & Deep Learning
Mass Spectrometry Analysis
Statistical Modeling & Experimental Design
Pipeline Development & Automation
Team Leadership & Mentorship

Services

🧬 Metabolomics & Proteomics

Comprehensive metabolomics and proteomics data analysis including statistical modeling, biomarker discovery, and pathway enrichment. Expert support for LC-MS, GC-MS, and DIA proteomics workflows.

📊 Statistical Analysis

Advanced statistical modeling including multivariate analysis, mixed-effects models, Bayesian inference, and experimental design optimization for large-scale omics studies.

🎯 Target Selection

Data-driven target identification and validation using multi-omics integration, machine learning approaches, and structural analysis for drug discovery programs.

🤖 AI Integration

Implementing cutting-edge AI and machine learning solutions including NLP/LLM methods (RAG), deep learning for peak detection, and automated data pipelines for research acceleration.

⚙️ Workflow Automation

Building automated data pipelines, cloud-based analysis platforms, and custom bioinformatics solutions to optimize research workflows and reduce operational costs.

🔬 Custom Analysis Solutions

Tailored bioinformatics solutions for your specific research needs, from proof-of-principle analyses to production-scale data platforms.